GMOD

Zheng’s installation notes

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general information

There suppose to be an easy way and a hard way to install Chado database on Fedora:

before you start

get chado schema from cvs

see Chado From CVS, issue cvs command at my home directory.

install prerequisites

install <a href=”http://en.wikipedia.org/wiki/Apache_Ant” class=”external text”

rel=”nofollow”>Ant</a></span>

sudo yum install ant

install <a href=”http://www.postgresql.org/” class=”external text”

rel=”nofollow”>postgresql</a></span>

[zha@localhost ~] sudo yum install postgresql
[zha@localhost ~] sudo yum install postgresql-server

right now the version is 8.1.8 (in yum package pool)

[zha@localhost ~] sudo /sbin/service postgres start

to make it run at boot

[zha@localhost ~] sudo /sbin/chkconfig postgres on
export PGDATA="/var/lib/pgsql/data/"

But I still can’t get rid of the -D /var/lib/pgsql/data/ why???

[zha@localhost gff3]$ sudo -u postgres postgres
postgres does not know where to find the server configuration file.
You must specify the --config-file or -D invocation option or set the PGDATA environment variable.
[zha@localhost gff3]$ sudo -u postgres postgres -D /var/lib/pgsql/data
FATAL:  lock file "postmaster.pid" already exists
HINT:  Is another postmaster (PID 2785) running in data directory "/var/lib/pgsql/data"?
[zha@localhost ~] sudo -u postgres creatlang plpgsql template1
[zha@localhost ~] sudo -u postgres createuser zha

replace zha with your own account name at your home directory. this must be a user with privilege to create and drop database. this is purely for the purpose of smooth installation.

[zha@localhost ~] sudo -u postgres createuser root

this must be a superuser of postgresql (same privilege as postgres), this is for installing DBIx::DBStag.

the pg_hba.conf is in /var/lib/pgsql/data/pg_hba.conf, you probably need to chown to postgres.

# TYPE  DATABASE    USER        CIDR-ADDRESS          METHOD
local   all         all                               trust
host    all         all         127.0.0.1/32          trust
host    all         all         ::1/128               trust

need revisit for local access and access method (MD5)

haven’t done yet.

install several general perl modules

use sudo cpan to do it. install

CGI (GBrowse)

GD (GBrowse)

DBI (GBrowse,chado)

DBD::Pg (1.49 or better) (GBrowse,chado)

you can also install it by

yum install perl-DBD-Pg

Digest::MD5 (GBrowse)

Text::Shellwords (GBrowse)

Data::Stag (chado)

XML::Parser::PerlSAX (chado)

Module::Build (chado)

Class::DBI (GMODWeb, or with a custom Chado schema)

Class::DBI::Pg (GMODWeb, or with a custom Chado schema)

Class::DBI::Pager (GMODWeb, or with a custom Chado schema)

DBIx::DBStag (chado)

XML::Simple (chado)

LWP (chado)

Template (chado)

Log::Log4perl (chado)

Term::ProgressBar (2.06 or better) (chado)

install <a href=”http://search.cpan.org/~sendu/bioperl-1.5.2_102/”

class=”external text” rel=”nofollow”>bioperl live</a></span>

[zha@localhost ~]$ sudo cpan
Password:
cpan[1]> install S/SE/SENDU/bioperl-1.5.2_102

this is the live bioperl right now

install <a href=”http://sourceforge.net/projects/geneontology”

class=”external text” rel=”nofollow”>go-dev</a></span>

download and unpack the go-dev package since need to set the GO_ROOT environment variable. Although right now only a perl parser module for GO is needed.

export GO_ROOT="$HOME/go-dev"
[zha@localhost ~]$ sudo cpan
Password:
cpan[1]> install GO::Parser

install chado

export GMOD_ROOT="/usr/local/gmod"
export CHADO_DB_NAME="yeast_chado"
export CHADO_DB_USERNAME="zha"
perl Makefile.PL
make
sudo make install

and then:

make load_schema
make prepdb
make ontologies
pg_dump wormbase_chado > onto_only.sql

download yeast genome gff3 file. load by bulk load

gmod_bulk_load_gff3.pl --organism yeast --gfffile saccharomyces_cerevisiae.gff

install gbrowse to work with chado

download Gbrowse, unpack it. standard install procedure. But be sure to read README.fedora and disable SELINUX for apache!!!

perl Makefile.PL HTDOCS=/var/www/html CONF=/etc/httpd/conf CGIBIN=/var/www/cgi-bin --SELINUX=1
make
sudo make install UNINST=1

who is running apache?

[zha@localhost ~]$ ps -ef |grep httpd

in my machine it is ‘apache’. configure gbrowse to work with chado.

cp /home/zha/Generic-Genome-Browser-1.67/contrib/conf_files/07.chado.conf /etc/httpd/conf/gbrowse.conf/yeast_chado.conf

make two-line-change to yeast_chado.conf

database      = dbi:Pg:dbname=yeast_chado;host=localhost;port=5432
user          = apache

grant select privilege on several tables to apache

grant select on feature to apache;

in Mac it is www, see Jim’s installation notes.

it is a little bit surprise to me that I need

grant select on analysisfeature to apache;

since no analysisfeature exists in dataset (?)

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