GMOD

Bio GMOD GenericGenePage

Bio%253A%253AGMOD::GenericGenePage is an abstract Perl class that provides a render_xml method to crete Common Gene Page XML, but does not fetch the data. In order to effectively use this module, you need to subclass it and implement all of the methods that are listed under ABSTRACT CLASSES below for your database. These abstract methods are responsible for providing Bio%253A%253AGMOD::GenericGenePage with the data to create the XML.

There are two example implementations included with this module. Bio%253A%253AGMOD::GenericGenePage::Chado is a simple implementation for a Chado database populated with S. cerevisiae data obtained from SGD as GFF3. Currently, the output of this implementation can be seen at

http://gmod.org/cgi-bin/gbrowse/chado_yeast/

and by clicking on any of the genes (red arrows).

The other implementation, CXGN::Phenome::GenericGenePage, is from SGN, the Sol Genomics Network. The XML they provide can be seen by clicking on the “Download GMOD XML” link on any of there locus pages; for example, this one:

http://sgn.cornell.edu/phenome/locus_display.pl?locus_id=1238

For more information see http://gmod.org/wiki/Bio_GMOD_GenericGenePage or contact Scott Cain, scain@cpan.org.

While there is no example CGI included in this distribution that show how this module can be used, that could be included in future distribution if there is interest in it.

FlyBase implementation

http://flybase.org/genome/Drosophila_melanogaster/current/genepage/FBgn0000490

EcoliWiki implementation

The EcoliWiki implementation is written as a REST-like service in PHP.

http://ecoliwiki.net/rest/gmod_gene.php/gene_symbol/pfkA

See the discussion page for issues arising.

Abstract Classes

Methods below should be overridden by each GenericGenePage implementation.

 name
     Usage: my $name = $genepage->name();
     Desc : get the string name of this gene
     Args : none
     Ret  : string gene name, e.g. 'Pax6'
     Side Effects: none

 accessions
     Usage: my @accessions = $genepage->accessions();
     Desc : get a list of local accession values
     Args : none
     Ret  : a list of local accessions
     Side Effects: none
   Note that these are the accessions that are used by the MOD providing
   the information, not accessions in external databases like GenBank.

 data_provider
     Usage: my $data_provider = $genepage->data_provider();
     Desc : The name of the data providing authority (ie, WormBase, SGD, etc)
     Args : none
     Ret  : string, name of the data provider
     Side Effects: none

 synonyms
     Usage: my @syn = $genepage->synonyms();
     Desc : get a list of synonyms for this gene
     Args : none
     Ret : list of strings,
           e.g. (  '1500038E17Rik',
                   'AEY11',
                   'Dey',
                   "Dickie's small eye",
                   'Gsfaey11',
                   'Pax-6',
                )
     Side Effects: none

 map_locations
     Usage: my @locs = $genepage->map_locations()
     Desc : get a list of known map locations for this gene
     Args : none
     Ret  : list of map locations, each a hashref as:
            {  map_name => string map name,
               chromosome => string chromosome name,
               marker     => (optional) associated marker name,
               position   => numerical position on the map,
               units      => map units, either 'cm', for centimorgans,
                             or 'b', for bases
            }
     Side Effects: none

 ontology_terms
     Usage: my @terms = $genepage->ontology_terms();
     Desc : get a list of ontology terms
     Args : none
     Ret  : hash-style list as:
              termname => human-readable description,
     Side Effects: none
     Example:
        my %terms = $genepage->ontology_terms()
        # and %terms is now
        (  GO:0016711 => 'F:flavonoid 3'-monooxygenase activity',
           ...
        )
   Note that the value in that has is the the concatenation of F:, B: or C:
   for molecular_function, biological_process, or cellular_component GO
   terms respectively. If the term does not belong to GO, there is no
   prepended identifier.

 dbxrefs
     Usage: my @dbxrefs = $genepage->dbxrefs();
     Desc : get a list of database cross-references for info related to this gene
     Args : none
     Ret  : list of strings, like type:id e.g. ('PFAM:00012')
     Side Effects: none

 comments
     Usage: my @comments = $genepage->comments();
     Desc : get a list of comments with types
     Args : none
     Ret  : a hash of comment=>type, where type is optional (empty string)
     Side Effects: none

 literature_references
     Usage: my @refs = $genepage->lit_refs();
     Desc : get a list of literature references for this gene
     Args : none
     Ret  : list of literature reference identifers, as type:id,
            like ('PMID:0023423',...)
     Side Effects: none

 summary_text
     Usage: my $summary = $page->summary_text();
     Desc : get a text string of plain-English summary text for this gene
     Args : none
     Ret  : string of summary text
     Side Effects: none

 organism
     Usage: my $species_info = $genepage->organism
     Desc : get a handful of species-related information
     Args : none
     Ret  : hashref as:
            { ncbi_taxon_id => ncbi taxon id, (e.g. 3702),
              binomial      => e.g. 'Arabidopsis thaliana',
              common        => e.g. 'Mouse-ear cress',
            }
     Side Effects: none

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