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MAKER is a portable and easy to configure genome annotation pipeline that has just become a part of GMOD. It's purpose is to allow smaller eukaryotic genome projects to annotate their genomes and to create genome databases. MAKER identifies repeats, aligns ESTs and proteins to a genome, produces ab initio gene predictions and automatically synthesizes these data into gene annotations having evidence-based quality values. MAKER is also easily trainable: outputs of preliminary runs can be used to automatically retrain its gene prediction algorithm, producing higher quality gene-models on subsequent runs. MAKER's inputs are minimal. It outputs are in GFF3 or FASTA format, and can be directly loaded into Chado, GBrowse, and Apollo.

MAKER was created and is maintained by the Mark Yandell Lab at the University of Utah.

See MAKER for more on how you can use it to automatically annotate your genomic data.

Posted to the GMOD News on 2008/05/16