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Available on platformweb +, linux +, os x + and windows +
Has URLhttp://biocyc.org/download.shtml +, http://bioinformatics.ai.sri.com/ptools/ +, http://biocyc.org/ +, http://biocyc.org/ECOLI/ + and http://biocyc.org/otherpgdbs.shtml +
Has descriptionPathway Tools is a comprehensive symbolic Pathway Tools is a comprehensive symbolic systems biology software system that supports several use cases in bioinformatics and systems biology:
  • Development of organism-specific databases called Pathway/Genome Databases (PGDBs) that integrate many bioinformatics datatypes, from genomes to pathways to regulatory networks.
  • Development of metabolic-flux models using flux-balance analysis
  • Scientific visualization, web publishing, and dissemination of those organism-specific databases, including:
    • Automatic display of metabolic pathways and full metabolic networks; generation of metabolic map diagram and of metabolic map poster (example).
    • Genome browser; comparative genome browser; generation of genome poster (example).
    • Display of operons, regulons, and full transcriptional regulatory networks
  • Analysis of omics datasets, including painting omics data on to diagrams of the full metabolic network, enrichment analysis.
  • Computational inferences including prediction of metabolic pathways, prediction of metabolic pathway hole fillers, prediction of operons
  • Comparative analyses of model-organism databases.
  • Analysis of biological networks:
    • Interactively tracing metabolites through the metabolic network
    • Finding dead-end metabolites in metabolic networks
    • Identifying choke points (potential drug targets) in metabolic networks

Pathway Tools has four components:

  • PathoLogic: Creates a new PGDB containing the predicted metabolic pathways of an organism, given a Genbank entry as input.
  • Pathway/Genome Navigator: Supports query, visualization, and analysis of PGDBs. The Navigator powers the BioCyc web site at BioCyc.org.
  • MetaFlux: Supports development of metabolic flux models from Pathway/Genome Databases.
  • Pathway/Genome Editors: Provide interactive editing capabilities for PGDBs.nteractive editing capabilities for PGDBs. + and list of PGDBs hosted elsewhere +
Has development statusactive +
Has download URLhttp://biocyc.org/download.shtml +
Has input formatGenbank format + and GFF +
Has logoPathwayTools.png +
Has output formatGenbank format +, SBML + and BioPAX +
Has software maturity statusmature +
Has support statusactive +
Has titleE. coli PGDB + and Other PGDBs +
Has topicPathway Tools +
Has websitehttp://bioinformatics.ai.sri.com/ptools/ +
Is open sourceCaveats apply +
Link typedownload +, website +, public server + and wild URL +
Release date1999 +
Tool functionality or classificationCommunity Annotation +, Comparative Genome Visualization +, Database schema +, Database tools +, Gene Expression Visualization +, Genome Visualization & Editing +, Molecular Pathway Visualization + and Ontology Visualization +
Has subobjectThis property is a special property in this wiki.Pathway Tools#http://biocyc.org/download.shtml +, Pathway Tools#http://bioinformatics.ai.sri.com/ptools/ +, Pathway Tools#http://biocyc.org/ +, Pathway Tools#http://biocyc.org/ECOLI/ + and Pathway Tools#http://biocyc.org/otherpgdbs.shtml +