GBrowse
GBrowse[1] is the most popular viewer in GMOD. For a list of GBrowse and GMOD installations see the GMOD Users page. For a demo of its features, try the WormBase, FlyBase, or Human Genome Segmental Duplication Database web sites.
Note: The current stable version of Gbrowse is version 1.69. The pre-release source code is available from CVS under the 'stable' branch.
Contents
Description
The Generic Genome Browser is a combination of database and interactive Web page for manipulating and displaying annotations on genomes. Some of its features:
- Simultaneous bird's eye and detailed views of the genome.
- Scroll, zoom, center.
- Use a variety of premade glyphs (see the BioPerl Glyph documentation for a list) or create your own.
- Attach arbitrary URLs to any annotation.
- Order and appearance of tracks are customizable by administrator and end-user.
- Search by annotation ID, name, or comment.
- Supports third party annotation using GFF formats.
- Settings persist across sessions.
- DNA and GFF dumps.
- Connectivity to different databases, including BioSQL and Chado.
- Multi-language support.
- Third-party feature loading.
- Customizable plug-in architecture (e.g. run BLAST, dump & import many formats, find oligonucleotides, design primers, create restriction maps, edit features)
Installation
GBrowse is Perl-based. It can be installed using the standard Perl module build procedure, or automated using a network-based install script. You will need to have Perl 5.8.6 or higher, and the Apache web server installed. See the step-by-step instructions below for detailed instructions:
- Install on MacOSX
- Install on Windows
- Install on Ubuntu and other Debian-based systems
- Install on Fedora Core and other RPM-based systems
- Install on Gentoo Linux system
- Source Code Install (for other Linux systems)
Documentation
On-line documentation
- GBrowse Tutorial
- GBrowse source code installation HOWTO
- GBrowse configuration HOWTO
- Generic-Genome-Browser/htdocs/general_help.html
- Generic-Genome-Browser/htdocs/annotation_help.html
- GBrowse Popup Balloons
- GBrowse FAQ
POD documentation
There are many useful POD documents included with the distribution. These are converted to HTML files when you install the package, and can be found in /gbrowse/docs/pod:
- Generic-Genome-Browser/docs/pod/BIOSQL_ADAPTER_HOWTO.pod
- Generic-Genome-Browser/docs/pod/GENBANK_HOWTO.pod
- Generic-Genome-Browser/docs/pod/PLUGINS_HOWTO.pod
- Generic-Genome-Browser/docs/pod/CONFIGURE_HOWTO.pod
- Generic-Genome-Browser/docs/pod/INSTALL.MacOSX.pod
- Generic-Genome-Browser/docs/pod/DAS_HOWTO.pod
- Generic-Genome-Browser/docs/pod/INSTALL.pod
- Generic-Genome-Browser/docs/pod/README-chado.pod
- Generic-Genome-Browser/docs/pod/FAQ.pod
- Generic-Genome-Browser/docs/pod/MAKE_IMAGES_HOWTO.pod
- Generic-Genome-Browser/docs/pod/README-gff-files.pod
- Generic-Genome-Browser/docs/pod/GBROWSE_IMG.pod
- Generic-Genome-Browser/docs/pod/ORACLE_AND_POSTGRESQL.pod
- Generic-Genome-Browser/docs/pod/README-lucegene.pod
Since these are in Perl POD format these files may contain formatting code when viewed in a Web browser.
Downloads
Source Code Download (tar.gz file)
Download the source from the SourceForge download page.
Net-based Installer Script
The net installer script, located at the GBrowse CVS repository will automatically download and install GBrowse and its Perl libraries for you. See Installation for details on using this script.
CVS
There are many new features in the current development version which have not been released yet. To get the latest version, please use anonymous CVS. The recommended branch to use is stable which is more stable than HEAD. Here is the recipe:
% cvs -d :pserver:anonymous@gmod.cvs.sourceforge.net:/cvsroot/gmod login CVS password: <hit return> % cvs -d :pserver:anonymous@gmod.cvs.sourceforge.net:/cvsroot/gmod co -r stable Generic-Genome-Browser
Once you have successfully checked out the Generic-Genome-Browser distribution, you can simply perform a cvs update
inside the directory to get recent changes.
You can also browse the GBrowse CVS.
About Databases
GBrowse has a flexible adaptor system for running off various types of database. Standard adaptors include:
- Flat file adaptors (in-memory, indexed) -- put your annotations in a directory and go!
- Relational database adaptors -- Chado, BioSQL.
- Network adaptors -- read annotations from GenBank, UCSC or Ensembl.
- GFF databases -- Bio::DB::GFF, Bio::DB::SeqFeature
Contacts
Please report bugs to the SourceForge Bug Tracker.
Please send questions to the GBrowse mailing list.
References
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